Physical Models of Blood Vessel Formation
نویسنده
چکیده
Understanding the mechanism of blood vessel formation has been an important subject in recent medical research. Various experiments and models have been proposed, yet fully understanding the mechanism has been challenging. This paper is meant to be a brief description of experimental results and methods of modeling the blood vessel formation. Models are compared with experimental data for the process of both vasculogenesis and angiogenesis to discuss how physical assumptions in the models lead to the understanding of biological mechanism.
منابع مشابه
Modelling Tumor-induced Angiogenesis: Combination of Stochastic Sprout Spacing and Sprout Progression
Background: Angiogenesis initiated by cancerous cells is the process by which new blood vessels are formed to enhance oxygenation and growth of tumor. Objective: In this paper, we present a new multiscale mathematical model for the formation of a vascular network in tumor angiogenesis process. Methods: Our model couples an improved sprout spacing model as a stochastic mathematical model of spro...
متن کاملModeling angiogenesis: A discrete to continuum description.
Angiogenesis is the process by which new blood vessels develop from existing vasculature. During angiogenesis, endothelial tip cells migrate via diffusion and chemotaxis, loops form via tip-to-tip and tip-to-sprout anastomosis, new tip cells are produced via branching, and a vessel network forms as endothelial cells follow the paths of tip cells. The latter process is known as the snail trail. ...
متن کاملComparing the Effects of Plyometric Training with and without Vessel Occlusion on Electromyographic Parameters
Purpose: Doing plyometric training with and without the vessel occlusion is an effective practice for rapid increase of muscles strength their hypertrophy. We evaluated the effects of plyometric training with and without the vessel occlusion on electromyographic parameters. Methods: In this quasi-experimental study, 22 females were selected through convenience sampling method. They were random...
متن کاملStudy of Pulsatile Non-Newtonian Blood Flow Through Abdominal Aorta and Renal Arteries Incorporating Fluid- Structure Interaction
Background: The interaction between the blood and the vessel wall is of great clinical interest in studying cardiovascular diseases, the major causes of death in developed countries.Objective: To understand the effects of incorporating fluid-structure interaction into the simulation of blood flow through an anatomically realistic model of abdominal aorta and renal arteries reconstructed from CT...
متن کاملImpact of Blood Vessel Wall Flexibility on the Temperature and Concentration Dispersion
The analysis of solute and thermal dispersion in pulsatile flow through the stenotic tapered blood vessel is presented. The present problem is an extension of the work done by Ramana et al. who considered the time-invariant arterial wall. In the present model, the flexible nature of the arterial wall through the obstruction (called stenosis) is considered and it is achieved with the he...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2008